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Single-cell RNA sequencing of MCF-7 cells treated with 17-β estradiol or fulvestrant, and fulvestrant resistant derivatives of MCF-7 cells

GSE306192 Homo sapiens Expression profiling by high throughput sequencing 7 samples Submitted 2025/11/24 Platform GPL21697
Summary
Single-cell RNA sequencing (scRNA-seq) on MCF-7 breast cancer cells treated with fulvestrant or 17-β estradiol, and MCF-7 cell line derivatives made resistant to fulvestrant.
Published in
Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of P-Rex1/Rac1 signalling
Fernandez KJ, Sultani G, Nobis M et al. · Nature communications 2026 · PMID 42115169 · doi:10.1038/s41467-026-70683-x
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Also filed as BioProject PRJNA1309665 and SRA study SRP610900. Searching any of these in the dataset finder brings you back here.

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