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SPP1+ Macrophages Contribute to Hair Growth in Contact Hypersensitivity [bulk RNA-Seq]

GSE306509 Mus musculus Expression profiling by high throughput sequencing 18 samples 2025/12/01 GPL24247
Summary
Transcriptomic analysis of sorted HFSCs revealed dynamic transcriptional reprogramming during inflammation, including activation of stress response and immune-modulatory genes. Pathway enrichment highlighted metabolic adaptation and signaling networks linked to stem cell activation. These findings demonstrate that HFSCs undergo intrinsic molecular changes that parallel their regenerative response.
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