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Clinical, genomic, and spatial transcriptomic features of pancreatic adenosquamous carcinoma

GSE306617 Homo sapiens (human) Other 11 samples Submitted 2026/08/11 Platform GPL24676
At a glance

human · 11 samples

Organism
Homo sapiens (human)
Topic
Pancreatic cancerThis series is part of our curated briefing on it.
Samples
11 samples: 11 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed table (series matrix) and supplementary files from NCBI.
Summary (written by the submitters)
Pancreatic adenosquamous carcinoma (PASC) is a rare and aggressive disease variant, accounting for 1-4% of all exocrine pancreatic malignancies. Compared to conventional pancreatic ductal adenocarcinoma (PDAC), the clinical and molecular characteristics of PASC remain poorly defined due to its understudied nature. To investigate the spatial biology of PASC, we profiled resected tissue specimens from patients in our institutional cohort using the Visium spatial transcriptomics platform for compartment-specific differential gene expression and pathway enrichment analyses.
This dataset
Download · which file do I need?

Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need.

All supplementary files ↗
3 · The original raw files

Whole study · RAW.tar

Everything the authors deposited as one archive (GSE306617_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.

Also filed as BioProject PRJNA1311486. Searching any of these in the dataset finder brings you back here.

Study design
11 samples, each with a distinct title — no replicated groups

Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.

How we read this: Read from 11 sample titles: 11 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.