Age-associated G-quadruplex accumulation and DDX5 loss shape chromatin landscapes in human astrocytes [RNA-seq]
RNA-seq (gene expression) · human · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 10 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Age-associated G-quadruplex accumulation and DDX5 loss shape chromatin landscapes in human astrocytesResearch square · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE307272_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1315127 and SRA study SRP617522. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 10 more — browse all 10 samples with per-sample file links →
- GSE307273 Age-associated G-quadruplex accumulation and DDX5 loss shape chromatin landscapes in human astrocytes [ATAC-seq] 16 samples shares ddx5, age-associated, g-quadruplex, accumulation, landscapes, astrocytes, chromatin
- GSE307274 Age-associated G-quadruplex accumulation and DDX5 loss shape chromatin landscapes in human astrocytes [CUT&Tag] 16 samples shares ddx5, age-associated, g-quadruplex, accumulation, landscapes, astrocytes, chromatin
- GSE283485 G-quadruplexes regulate chromatin accessibility and gene expression in Bloom Syndrome [RNA-seq] 24 samples shares g-quadruplex, chromatin, rna-seq
- GSE281517 Lysosomal sequestration of PARP inhibitors drives heterogeneous accumulation in ovarian cancer to increase efficacy [RNA-seq] 72 samples shares accumulation, rna-seq
- GSE250293 G-quadruplexes within the SVA retrotransposon modulate TAF1 gene expression in X-linked Dystonia Parkinsonism [RNA-Seq] 63 samples shares g-quadruplex, rna-seq
- GSE261563 G-quadruplex stabilizer CX-5461 effectively combines with ionizing radiation to selectively target ATRX-deficient malignant glioma [RNA-seq] 30 samples shares g-quadruplex, rna-seq
- GSE279501 G-quadruplex structures regulate long-range transcriptional reprogramming to promote drug resistance in ovarian cancer [RNA-seq] 24 samples shares g-quadruplex, rna-seq
- GSE289971 m6A Methylation Suppresses anti-tumour immune responses in Colorectal Cancers by Inhibiting Double-stranded RNA accumulation from Alu Repeats [RNA-Seq1] 16 samples shares accumulation, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.