Inhibiting Glycan Degradation Prevents HIV-Induced Inflammaging and Cognitive Impairment
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE308269_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1329335 and SRA study SRP620873. Searching any of these in the dataset finder brings you back here.
The grouping that defines any comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Sample titles run STL6520 … STL6558 and carry no group information.
- GSM9241444 STL6520
- GSM9241445 STL6521
- GSM9241446 STL6522
- GSM9241447 STL6523
- GSM9241448 STL6532
- GSM9241449 STL6533
- GSM9241450 STL6534
- GSM9241451 STL6535
- GSM9241452 STL6544
- GSM9241453 STL6545
- GSM9241454 STL6546
- GSM9241455 STL6547
- GSM9241456 STL6555
- GSM9241457 STL6556
- GSM9241458 STL6557
- GSM9241459 STL6558
- GSE299728 Urolithin A maintains primordial follicle dormancy and prevents cyclophosphamide-induced follicle loss by inhibiting the PI3K/Akt signaling 12 samples shares inhibiting, prevents
- GSE224756 Redox sensor KEAP1 promotes stemness and prevents reductive stress in exhausted CD8+ T cells via inhibiting NRF2 18 samples shares inhibiting, prevents
- GSE297515 Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging 90 samples shares inflammaging
- GSE260522 Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development [RNA-seq] 86 samples shares degradation
- GSE319035 P21+TREM2+-Senescent Macrophages Fuel Inflammaging and Metabolic Dysfunction-Associated Steatotic Liver Disease [NAFLD_time_course] 77 samples shares inflammaging
- GSE301303 Targeted KRAS G12V degradation elicits efficient and durable lung adenocarcinoma regression in vivo 65 samples shares degradation
- GSE289371 Chemically-induced protein degradation reveals inflammation-dependent requirement for Treg lineage-defining transcription factor FOXP3 58 samples shares degradation
- GSE297833 ChAHP Silences SINE Retrotransposons by Inhibiting TFIIIB Recruitment [RNA-seq] 54 samples shares inhibiting
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.