Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma [RNA-Seq]
Single-cell RNA-seq · human · 246 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart. Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Homo sapiens (human)
- Samples
- 246 samples: 211 distinct titles, 35 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric AsthmabioRxiv : the preprint server for biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE309698_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1336779 and SRA study SRP630133. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 246 sample titles: 211 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9277327 1_T188
- GSM9277328 3_T188
- GSM9277329 5_T188
- GSM9277330 6_T188
- GSM9277331 8_T188
- GSM9277332 10_T168
- GSM9277333 12_T168
- GSM9277334 14_T168
- GSM9277335 15_T168
- GSM9277336 17_T168
- GSM9277337 19_T192
- GSM9277338 21_T192
- GSM9277339 23_T192
- GSM9277340 26_T192
- GSM9277341 28_T182
- GSM9277342 30_T182
- GSM9277343 32_T182
- GSM9277344 33_T182
- GSM9277345 35_T182
- GSM9277346 37_T193
- GSM9277347 39_T193
- GSM9277348 41_T193
- GSM9277349 42_T193
- GSM9277350 44_T193
- GSM9277351 46_T191
- GSM9277352 48_T191
- GSM9277353 50_T191
- GSM9277354 51_T191
- GSM9277355 53_T191
- GSM9277356 55_T190
- GSM9277357 57_T190
- GSM9277358 59_T190
- GSM9277359 60_T190
- GSM9277360 62_T190
- GSM9277361 64_T194
- GSM9277362 66_T194
- GSM9277363 68_T194
- GSM9277364 69_T194
- GSM9277365 71_T194
- GSM9277366 73_T170
+ 206 more — browse all 246 samples with per-sample file links →
- GSE309311 Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma [scRNA-Seq] 28 samples shares exacerbation-prone, dysregulated, epithelium, interferon, rhinovirus, bronchial, pediatric, rna-seq
- GSE309705 Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma 274 samples shares exacerbation-prone, dysregulated, epithelium, interferon, rhinovirus, bronchial, pediatric
- GSE281833 RNA-Sequencing Analysis of Type-I and Type-II Interferon Effects on an In-Vitro Human Thymic Epithelium Model 24 samples shares epithelium, interferon, rna-seq
- GSE302095 Validation of bronchial airway gene expression associated with bronchiectasis in nasal epithelium 132 samples shares epithelium, bronchial
- GSE298908 Positionally distinct interferon-stimulated dermal immune-acting fibroblasts promote neutrophil recruitment in Sweet's syndrome [RNA-seq] 113 samples shares interferon, rna-seq
- GSE314922 Immune-microbiome coordination defines interferon setpoints in healthy humans [bulk RNA-seq] 108 samples shares interferon, rna-seq
- GSE243339 Clues to Drivers of Juvenile Dermatomyositis: Genetic Alterations after Type I Interferon and JAK Inhibitor Treatment in Pediatric Bioengineered Skeletal Muscle 83 samples shares interferon, pediatric
- GSE288674 Interferon regulatory factor 4 mediates non-enzymatic IRE1 dependency in multiple myeloma cells [RNA-Seq] 45 samples shares interferon, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.