SETDB1/HUSH modulates Xist RNA levels during establishment of X chromosome inactivation [RNA-Seq]
RNA-seq (gene expression) · mouse · 112 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 112 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- SETDB1 and HUSH modulate Xist RNA levels during establishment of X chromosome inactivationNature communications · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE310108_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1365147 and SRA study SRP645406. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 112 more — browse all 112 samples with per-sample file links →
- GSE309424 SETDB1/HUSH modulates Xist RNA levels during establishment of X chromosome inactivation 292 samples shares setdb1, hush, establishment, inactivation, chromosome, modulates, levels
- GSE309423 SETDB1/HUSH modulates Xist RNA levels during establishment of X chromosome inactivation [ChIP-Seq] 42 samples shares setdb1, hush, establishment, inactivation, chromosome, modulates, levels
- GSE206159 Stepwise de novo establishment of inactive X chromosome architecture in early development [Embryo RNA-seq] 42 samples shares establishment, chromosome, rna-seq
- GSE206179 Stepwise de novo establishment of inactive X chromosome architecture in early development [XEN cells RNA-seq] 32 samples shares establishment, chromosome, rna-seq
- GSE295196 m6A RNA methylation in the maintenance of X-chromosome inactivation and X to autosome dosage compensation in early embryogenesis [RNA-Seq] 14 samples shares inactivation, chromosome, rna-seq
- GSE232546 Exploring the Stability of Genomic Imprinting and X-Chromosome Inactivation in the Aged Brain (RNA-Seq) 11 samples shares inactivation, chromosome, rna-seq
- GSE275353 Exploring the Mechanism of SETDB1 in Regulating Neuroinflammation and Anxiety-Depression-like Behaviors [RNA-seq] 19 samples shares setdb1, rna-seq
- GSE266388 Histone methyltransferase SETDB1 safeguards mouse fetal hematopoiesis by suppressing activation of cryptic enhancers [RNA-seq] 12 samples shares setdb1, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.