Regulation of murine follicle-stimulating hormone β subunit transcription by newly identified enhancers
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 27 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 27 samples: 12 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Regulation of murine follicle-stimulating hormone β subunit transcription by newly identified enhancersbioRxiv : the preprint server for biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE310461_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1366359 and SRA study SRP646814. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 5 samples read as cases, 11 as controls.
How we read this: 12 replicated groups read from 27 sample titles; they account for 26 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9301702 LbT2b_vehicle_rep_1 LbT2b_vehicle
- GSM9301703 LbT2b_vehicle_rep_2 LbT2b_vehicle
- GSM9301704 LbT2b_activin_rep_1 LbT2b_activin
- GSM9301705 LbT2b_activin_rep_2 LbT2b_activin
- GSM9301706 vehicle_FLAG_IP_REP1 vehicle_FLAG_IP
- GSM9301707 vehicle_H3K27_IP_REP1 vehicle_H3K27_IP
- GSM9301708 vehicle_SMAD2_3_IP_REP1 vehicle_SMAD2_3_IP
- GSM9301709 vehicle_FLAG_IP_REP2 vehicle_FLAG_IP
- GSM9301710 vehicle_H3K27_IP_REP2 vehicle_H3K27_IP
- GSM9301711 vehicle_SMAD2_3_IP_REP2 vehicle_SMAD2_3_IP
- GSM9301712 activin_FLAG_IP_REP1 activin_FLAG_IP
- GSM9301713 activin_H3K27_IP_REP1 activin_H3K27_IP
- GSM9301714 activin_SMAD2_3_IP_REP1 activin_SMAD2_3_IP
- GSM9301715 activin_FLAG_IP_REP2 activin_FLAG_IP
- GSM9301716 activin_H3K27_IP_REP2 activin_H3K27_IP
- GSM9301717 activin_SMAD2_3_IP_REP2 activin_SMAD2_3_IP
- GSM9301718 ProteinA_control
- GSM9301719 WildType_Mouse1 WildType_Mouse
- GSM9301720 Fshb-Enh2-KO_Mouse2 Fshb-Enh2-KO_Mouse
- GSM9301721 Fshb-Enh2-KO_Mouse3 Fshb-Enh2-KO_Mouse
- GSM9301722 WildType_Mouse4 WildType_Mouse
- GSM9301723 Fshb-Enh2-KO_Mouse5 Fshb-Enh2-KO_Mouse
- GSM9301724 IgG-treated_Mouse11 IgG-treated_Mouse
- GSM9301725 IgG-treated_Mouse12 IgG-treated_Mouse
- GSM9301726 Bimagrumab-treated_Mouse13 Bimagrumab-treated_Mouse
- GSM9301727 Bimagrumab-treated_Mouse14 Bimagrumab-treated_Mouse
- GSM9301728 Bimagrumab-treated_Mouse15 Bimagrumab-treated_Mouse
- GSE283958 Cohesin recruitment to promoters and enhancers by general transcription factors and chromatin regulators 47 samples shares transcription, enhancers
- GSE339012 Mega-Enhancers Compartmentalize Transcriptionally Active Long Genes in the Brain [ChIP-Seq] 22 samples shares transcription, enhancers
- GSE268172 Stable maintenance of MERVL-positive embryonic stem cells reveals sustained transcriptional programs and enhancer remodeling 45 samples shares transcription
- GSE326173 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [ChIP-seq] 42 samples shares transcription
- GSE294521 Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm [CUTnTAG] 34 samples shares transcription
- GSE324864 HP1B and H3K9me3 Regulate Olfactory Receptor Choice and 2 Transcriptional Identity [ChIP-seq] 28 samples shares transcription
- GSE281685 Transcription factor occupancy is affected by genetic variation in the white adipose tissue of C57BL6/j and 129S1/SvImJ mice [ChIP-seq] 16 samples shares transcription
- GSE305064 FOXP3 Expression Depends on Cell-Type Specific Cis-Regulatory Element and Transcription Factor Circuitry [mouse_Tconv_ChIP-seq] 15 samples shares transcription
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.