GEO series
Gene expression analysis using RNAseq upon SBNO1 knockdown in the HCC cell line Hep3B
GSE311232
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2026/04/15
GPL23227
Summary
Aberrant Notch signaling has been identified as a possible catalyst for hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) development. Genetic studies in Drosophila observed that the knockout of strawberry notch (sno) mimics loss of notch. Here, we elucidated the role of the mammalian Strawberry Notch 1 (SBNO1) in HCC and CCA development.
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Paper (PMID 41649174) ↗
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