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CALD1/IGF2BP1 complex mediates cisplatin resistance in bladder cancer via enhancing RFC4 mRNA stability in an m⁶A-dependent manner.

GSE313336 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/12/16 Platform GPL24676
Summary
Cisplatin-based chemotherapy is the first-line treatment for muscle-invasive and metastatic bladder cancer, but most patients develop drug resistance within a short period. M⁶A modification (N⁶-methyladenosine) has been extensively validated as a key hallmark of multiple cancers, and its dysregulation may contribute to cisplatin resistance.
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Direct links to NCBI, no account and no request form: the whole study as GSE313336_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1378984 and SRA study SRP654179. Searching any of these in the dataset finder brings you back here.

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