GEO series
Single-nuclei RNA-seq of meningioma
GSE313693
Homo sapiens
Expression profiling by high throughput sequencing
26 samples
2025/12/23
GPL24676
Summary
We applied single-nuclei RNA-seq to meningioma samples across grades and methylation classes, in order to characterize features of meningioma heterogeneity across subgroups. We identified an overall decrease in myeloid cell proportions from grade 1 to grade 3 meningiomas, as well as a phenotypic shift from microglia-like cells towards a myeloid-derived proliferative macrophage phenotype.
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Paper (PMID 41663806) ↗
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