Immune-microbiome coordination defines interferon setpoints in healthy humans
RNA-seq (gene expression) · human · 216 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 216 samples: 216 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Immune-microbiome coordination defines interferon setpoints in healthy humansCell · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE314923_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1393130 and SRA study SRP656586. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 216 sample titles: 216 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9396035 pool-1, well-1, GEX
- GSM9396036 pool-1, well-1, ADT
- GSM9396037 pool-1, well-2, GEX
- GSM9396038 pool-1, well-2, ADT
- GSM9396039 pool-1, well-3, GEX
- GSM9396040 pool-1, well-3, ADT
- GSM9396041 pool-1, well-4, GEX
- GSM9396042 pool-1, well-4, ADT
- GSM9396043 pool-10, well-1, GEX
- GSM9396044 pool-10, well-1, ADT
- GSM9396045 pool-10, well-2, GEX
- GSM9396046 pool-10, well-2, ADT
- GSM9396047 pool-10, well-3, GEX
- GSM9396048 pool-10, well-3, ADT
- GSM9396049 pool-10, well-4, GEX
- GSM9396050 pool-10, well-4, ADT
- GSM9396051 pool-11, well-1, GEX
- GSM9396052 pool-11, well-1, ADT
- GSM9396053 pool-11, well-2, GEX
- GSM9396054 pool-11, well-2, ADT
- GSM9396055 pool-11, well-3, GEX
- GSM9396056 pool-11, well-3, ADT
- GSM9396057 pool-11, well-4, GEX
- GSM9396058 pool-11, well-4, ADT
- GSM9396059 pool-12, well-1, GEX
- GSM9396060 pool-12, well-1, ADT
- GSM9396061 pool-12, well-2, GEX
- GSM9396062 pool-12, well-2, ADT
- GSM9396063 pool-12, well-3, GEX
- GSM9396064 pool-12, well-3, ADT
- GSM9396065 pool-12, well-4, GEX
- GSM9396066 pool-12, well-4, ADT
- GSM9396067 pool-13, well-1, GEX
- GSM9396068 pool-13, well-1, ADT
- GSM9396069 pool-13, well-2, GEX
- GSM9396070 pool-13, well-2, ADT
- GSM9396071 pool-13, well-3, GEX
- GSM9396072 pool-13, well-3, ADT
- GSM9396073 pool-13, well-4, GEX
- GSM9396074 pool-13, well-4, ADT
+ 176 more — browse all 216 samples with per-sample file links →
- GSE314416 Immune-microbiome coordination defines interferon setpoints in healthy humans [CITE-seq and WMS] 108 samples shares immune-microbiome, coordination, interferon, setpoints, defines, healthy, humans
- GSE314922 Immune-microbiome coordination defines interferon setpoints in healthy humans [bulk RNA-seq] 108 samples shares immune-microbiome, coordination, interferon, setpoints, defines, healthy, humans
- GSE299256 Positionally distinct interferon-stimulated dermal immune-acting fibroblasts promote neutrophil recruitment in Sweet's syndrome. 116 samples shares interferon
- GSE263931 Selective CAR-T cell mediated B cell depletion suppresses interferon signature in SLE [PBMC] 28 samples shares interferon
- GSE277387 Single-Cell and Spatial Multi-omics Reveal Interferon Signaling in the Pathogenesis of Perianal Fistulizing Crohn’s Disease 21 samples shares interferon
- GSE263932 Selective CAR-T cell mediated B cell depletion suppresses interferon signature in SLE [Bcells] 20 samples shares interferon
- GSE309140 Enhanced interferon-stimulated gene signatures in B cells following influenza B virus infection compared to influenza vaccination 16 samples shares interferon
- GSE317890 Transcriptomic profiling of interferon responses induced by IVT sgRNAs in CRISPRi HEK293T cells 360 samples shares interferon
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.