RXR binding pattern in human PMA-differentiated THP-1 cells upon ligand stimulation [RNA-seq]
RNA-seq (gene expression) · human · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 9 samples: 3 × hs_THP1_6h_vehicle_RNAseq vs 3 × hs_THP1_6h_Calcitriol_100nM_RNAseq vs 3 × hs_THP1_6h_combined_six_ligands_RNAseqGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Genome-wide chromatin profiling reveals a nonlimiting role for RXR in macrophage-like cells stimulated with multiple nuclear receptor agonistsThe Journal of biological chemistry · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE315572_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1398279 and SRA study SRP659741. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 3 replicated groups read from 9 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9431795 hs_THP1_6h_vehicle_RNAseq_rep1 hs_THP1_6h_vehicle_RNAs…
- GSM9431796 hs_THP1_6h_vehicle_RNAseq_rep2 hs_THP1_6h_vehicle_RNAs…
- GSM9431797 hs_THP1_6h_vehicle_RNAseq_rep3 hs_THP1_6h_vehicle_RNAs…
- GSM9431798 hs_THP1_6h_Calcitriol_100nM_RNAseq_rep1 hs_THP1_6h_Calcitriol_1…
- GSM9431799 hs_THP1_6h_Calcitriol_100nM_RNAseq_rep2 hs_THP1_6h_Calcitriol_1…
- GSM9431801 hs_THP1_6h_Calcitriol_100nM_RNAseq_rep3 hs_THP1_6h_Calcitriol_1…
- GSM9431802 hs_THP1_6h_combined_six_ligands_RNAseq_rep1 hs_THP1_6h_combined_six…
- GSM9431803 hs_THP1_6h_combined_six_ligands_RNAseq_rep2 hs_THP1_6h_combined_six…
- GSM9431804 hs_THP1_6h_combined_six_ligands_RNAseq_rep3 hs_THP1_6h_combined_six…
- GSE315571 RXR binding pattern in human PMA-differentiated THP-1 cells upon ligand stimulation [ChIP-seq] 28 samples shares thp-1, rxr, pma-differentiated, stimulation, binding, pattern, ligand
- GSE327840 RNA-seq profiling of LPS tolerance in monocytes, THP-1, fibroblasts, smooth muscle cells, and endothelial cells 58 samples shares thp-1, rna-seq
- GSE281531 Effect of depletion of MALAT1 on gene expression during LPS stimulation on THP-1 derived differentiated macrophages 24 samples shares thp-1, stimulation
- GSE327277 Bulk RNA-seq analysis of Delta-like 4 (Dll4) knockdown in LPS- or TNF-α-stimulated THP-1 cells 20 samples shares thp-1, rna-seq
- GSE268256 Transcriptional profiling of DNA sensing signal activation of THP-1 cells using bulk RNA-seq and single cell RNA-seq 17 samples shares thp-1, rna-seq
- GSE307944 RNA-seq of human THP-1 macrophages infected with adherent-invasive E. coli (AIEC) strains 12 samples shares thp-1, rna-seq
- GSE296019 RNA-seq of RSV-Infected THP-1 Cells Treated with Recombinant CTSC 12 samples shares thp-1, rna-seq
- GSE307844 RNA-seq of THP-1 and U937 exposed to enamel matrix derivative. 12 samples shares thp-1, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.