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Bulk RNA Sequencing of MCMV-Specific M45 Tetramer-Positive CD8⁺ T Cells from Wild-Type and B cell-deficient JHT mice

GSE315617 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/01/18 Platform GPL24247
Summary
To assess the impact of B cell deficiency on MCMV-specific CD8⁺ T cells, equal numbers of M45 tetramer-positive CD8⁺ T cells were sorted from wild-type and B cell–deficient JHT mice. The isolated antigen-specific CD8⁺ T cells were subjected to bulk RNA sequencing to compare transcriptional profiles between the two groups.
Published in
B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the antiviral CD8(+) T-cell response
Liu X, Demircik F, Antipova M et al. · Cellular & molecular immunology 2026 · PMID 41731129 · doi:10.1038/s41423-026-01392-0
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Also filed as BioProject PRJNA1398334 and SRA study SRP659790. Searching any of these in the dataset finder brings you back here.

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