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Genome-wide identification of transcriptional targets of H4K12 lactylation and GR in 786-O cells with or without dexamethasone treatment.

GSE315629 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 5 samples Submitted 2026/01/23 Platform GPL24676
Summary
To investigate the genome-wide transcriptional targets associated with H4K12 lactylation in renal cell carcinoma, cleavage under targets and tagmentation (CUT&Tag) was performed in 786-O cells with or without dexamethasone treatment using specific antibodies against H4K12 lactylation or GR. Following CUT&Tag, genomic DNA fragments were amplified under non-biased conditions and sequenced on the Illumina NovaSeq 150PE platform to generate high-resolution maps of H4K12 lactylation or GR–associated chromatin regions.
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Also filed as BioProject PRJNA1398355 and SRA study SRP659802. Searching any of these in the dataset finder brings you back here.

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