GEO series
A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture
GSE316956
Homo sapiens
Expression profiling by high throughput sequencing
31 samples
2026/03/13
GPL18573GPL11154
Summary
This dataset contains the RNA-seq data associated with a CRISPR/Cas9 study for which the screen results (sgRNA reads) are included in the GEO record GSE15547. Specifically, this dataset contains the RNA-seq results used to assess absolute gene expression in Nalm-6 cells, results for 3 PPP3CA knockout polulations, 3 PPP3R1 knockout populations, one FK-506 (tacrolimus) treated population and ERCC spike-in experiments on PABIR1 (formerly FAM122A) knockout cells, each with their own wild type and/or DMSO-treated control samples.
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Paper (PMID 41659671) ↗
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