GEO series
KAS-CUT&Tag for direct mapping of transcription bubbles
GSE317877
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
122 samples
2026/07/21
GPL34281
Summary
We introduce KAS-CUT&Tag, a method that combines N3-kethoxal labeling of exposed guanines with CUT&Tag to directly map Pol II at transcription bubbles. Pol II-induced bubbles are enriched at many highly-expressed genes, but the highest enrichment is at canonical histone genes in all phases of the cell cycle.
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NCBI GEO page ↗
Paper (PMID 42239153) ↗
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