← BioTransfer GEO Dataset Finder
GEO series

The role and mechanism of hypoxia-induced lncRNA in regulating ferroptosis in hepatocellular carcinoma

GSE318243 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/02/05 Platform GPL24676
Summary
One of the key alterations within solid tumors involves hypoxia, defined as oxygen tension below non-physiological levels. In liver cancer, hypoxia promotes disease progression through effects on cancer and non-cancer cells alike, impacting diverse processes including cell metabolism, proliferation, programmed cell death pathways, angiogenesis, metastasis, resistance to radiotherapy and systemic therapies.Consequently, defining how tumor cells benefit from reprogramming to survive challenging environmental conditions such as hypoxia has clear importance for identifying novel therapeutic targets and advancing treatments.In this study, we focus on the role of the hypoxia-responsive long noncoding RNA SHIELD in regulating ferroptosis in hepatocellular carcinoma.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE318243_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1416581 and SRA study SRP672048. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.