RNA-Seq quantitative analysis of the regulatory effects of plasma exosomes from CML patients on CML cell transcriptomes
RNA-seq (gene expression) · human · 13 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Chronic myeloid leukemiaThis series is part of our curated briefing on it.
- Samples
- 13 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE318881_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1420767 and SRA study SRP676124. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 13 more — browse all 13 samples with per-sample file links →
- GSE318329 RNA-Seq quantitative analysis of the regulation of imatinib-resistant cell-derived exosomes on CML cell transcriptomes 4 samples same disease briefing · shares cml, transcriptomes, quantitative, exosomes, rna-seq
- GSE247827 Single cell RNA-seq analysis of the effects of fluphenazine and/or nilotinib on primary CML CD34+CD38- cells 4 samples same disease briefing · shares cml, rna-seq
- GSE303378 Transcriptomic profiling of bone marrow cells from CML mouse models and newly diagnosed patients treated with SOS1 inhibitor BI-3406 and/or imatinib 48 samples same disease briefing · shares cml
- GSE337046 The distinct expression features between chronic phase and B-lymphoblastic crisis samples from patients with CML 37 samples same disease briefing · shares cml
- GSE276130 Gene expression profile at single cell level of LMPP (lymphoid-primed multipotent progenitor) cells from CP-CML and BC-CML patients. 6 samples same disease briefing · shares cml
- GSE309070 FBXO3-mediated DUSP9 ubiquitination reprograms MAPK signaling to eradicate tyrosine kinase inhibitor-resistant CML stem cells 6 samples same disease briefing · shares cml
- GSE333588 Single-cell mapping portrays the distinct expression features between chronic phase and B-lymphoblastic crisis samples from patients with CML 5 samples same disease briefing · shares cml
- GSE235463 Effect of knockdown PHF8 on the transcriptional regulation of BCR-ABL1 fusion gene on CML cell line K562 4 samples same disease briefing · shares cml
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.