Investigations into the aetiopathogenesis of orofacial granulomatosis using multiple omics technologies reveals a potential role for B cells
RNA-seq (gene expression) · human · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 16 samples: 9 × OFG patient vs 7 × Healthy controlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Investigations into the aetiopathogenesis of orofacial granulomatosis using multiple omics technologies reveal a potential role for B cellsClinical and translational medicine · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE320069_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1426338 and SRA study SRP678382. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 9 samples read as cases, 7 as controls.
How we read this: 2 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9533384 OFG patient 3 OFG patient
- GSM9533385 OFG patient 4 OFG patient
- GSM9533386 OFG patient 5 OFG patient
- GSM9533387 OFG patient 15 OFG patient
- GSM9533388 OFG patient 17 OFG patient
- GSM9533389 OFG patient 19 OFG patient
- GSM9533390 OFG patient 24 OFG patient
- GSM9533391 OFG patient 25 OFG patient
- GSM9533392 OFG patient 30 OFG patient
- GSM9533393 Healthy control 44 Healthy control
- GSM9533394 Healthy control 46 Healthy control
- GSM9533395 Healthy control 47 Healthy control
- GSM9533396 Healthy control 49 Healthy control
- GSM9533397 Healthy control 50 Healthy control
- GSM9533398 Healthy control 52 Healthy control
- GSM9533399 Healthy control 53 Healthy control
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.