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RNA-seq analysis of human corneal epithelial cells under hyperosmotic stress modeling dry eye disease

GSE323164 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/05/01 Platform GPL24676
Summary
We performed RNA-seq to investigate the transcriptomic changes in human corneal epithelial cells (HCECs) under hyperosmotic stress mimicking dry eye disease (DED).
Published in
Inhibition of SGK1 Alleviates Apoptosis and Oxidative Stress in Dry Eye Disease by Activating FoxO3a-Mediated Autophagy
Tang Y, Chen Z, Jiang J et al. · Investigative ophthalmology & visual science 2026 · PMID 42138516 · doi:10.1167/iovs.67.5.37
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Also filed as BioProject PRJNA1432064 and SRA study SRP681021. Searching any of these in the dataset finder brings you back here.

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