Hepatocytes promote liver metastasis of pancreatic cancer by providing exogenous serine, 2.
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE324997_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1438209 and SRA study SRP684135. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 5 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9590336 Hepatocytes only rep1 Hepatocytes only
- GSM9590337 Hepatocytes only rep2 Hepatocytes only
- GSM9590338 Hepatocytes only rep3 Hepatocytes only
- GSM9590339 Hepatocytes co-cultured with Phgdh WT cancer cells rep1 Hepatocytes co-cultured…
- GSM9590340 Hepatocytes co-cultured with Phgdh WT cancer cells rep2 Hepatocytes co-cultured…
- GSM9590341 Hepatocytes co-cultured with Phgdh WT cancer cells rep3 Hepatocytes co-cultured…
- GSM9590342 Hepatocytes co-cultured with Phgdh KO cancer cells rep1 Hepatocytes co-cultured…
- GSM9590343 Hepatocytes co-cultured with Phgdh KO cancer cells rep2 Hepatocytes co-cultured…
- GSM9590344 Hepatocytes co-cultured with Phgdh KO cancer cells rep3 Hepatocytes co-cultured…
- GSM9590345 Hepatocytes co-cultured with Phgdh WT cancer cells and CXCR2i rep1 Hepatocytes co-cultured…
- GSM9590346 Hepatocytes co-cultured with Phgdh WT cancer cells and CXCR2i rep2 Hepatocytes co-cultured…
- GSM9590347 Hepatocytes co-cultured with Phgdh WT cancer cells and CXCR2i rep3 Hepatocytes co-cultured…
- GSM9590348 Hepatocytes co-cultured with Phgdh KO cancer cells and CXCR2i rep1 Hepatocytes co-cultured…
- GSM9590349 Hepatocytes co-cultured with Phgdh KO cancer cells and CXCR2i rep2 Hepatocytes co-cultured…
- GSM9590350 Hepatocytes co-cultured with Phgdh KO cancer cells and CXCR2i rep3 Hepatocytes co-cultured…
- GSM9590352 Hepatocytes co-cultured with Phgdh KO cancer cells and CXCR2i rep4 Hepatocytes co-cultured…
- GSE324743 Hepatocytes promote liver metastasis of pancreatic cancer by providing exogenous serine 24 samples shares hepatocytes, metastasis, pancreatic, providing, exogenous, promote, serine, liver
- GSE266900 Cxcr3 promotes protection from colorectal cancer liver metastasis by driving NK infiltration and plasticity 18 samples shares metastasis, promote, liver
- GSE218178 Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance 183 samples shares pancreatic, promote
- GSE266918 RNA-seq expression analysis of liver, adipose, skeletal muscle, heart, and pancreatic islets from DO founder strain mice fed high-fat, high-sugar diet. [heart] 63 samples shares pancreatic, liver
- GSE266923 RNA-seq expression analysis of liver, adipose, skeletal muscle, heart, and pancreatic islets from DO founder strain mice fed high-fat, high-sugar diet. [liver] 61 samples shares pancreatic, liver
- GSE266920 RNA-seq expression analysis of liver, adipose, skeletal muscle, heart, and pancreatic islets from DO founder strain mice fed high-fat, high-sugar diet. [Adipose] 61 samples shares pancreatic, liver
- GSE285614 Adipocyte death drives fat redistribution from adipocytes to hepatocytes in steatotic liver disease via S100A8+ macrophages [RNA-seq] 34 samples shares hepatocytes, liver
- GSE328371 KMT2D depletion promote KRAS-induced pancreatic carcinogenesis independent of TP53 24 samples shares pancreatic, promote
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.