GEO series
Ceramide-induced Endoplasmic Reticulum Stress as a Targetable Vulnerability in Endocrine Therapy-Resistant Breast Cancer
GSE325086
Homo sapiens
Expression profiling by high throughput sequencing
24 samples
2026/05/15
GPL24676
Summary
10 µM C8-ceramide treated to endocrine therapy (ET) sensitive parental MCF-7 cells along with three of its ET-resistant derivative cell lines (MCF-7-HER2, MCF-7-TAMR, and MCF-7-FULR) for 24 hours. Total RNAseq was performed on triplicate samples from each group to compare C8-ceramide actions in ET-sensitive and ET-resistant breast cancer cells.
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