Antibody Mediated Diversification of Primary and Secondary Humoral Immune Responses
RNA-seq (gene expression) · mouse · 54 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 54 samples: 54 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Antibody-mediated diversification of primary and secondary humoral immune responsesThe Journal of experimental medicine · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE326797_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1447369 and SRA study SRP688886. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 54 sample titles: 54 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9640690 CD38+ B cell, M-only prime, GEX
- GSM9640691 CD38+ B cell, M-only prime, HTO
- GSM9640692 CD38+ B cell, M-only prime, BCR
- GSM9640693 GC B cell, M-only prime RBD neg, GEX
- GSM9640694 GC B cell, M-only prime RBD neg, HTO
- GSM9640695 GC B cell, M-only prime RBD neg, BCR
- GSM9640696 GC B cell, M-only prime RBD pos, GEX
- GSM9640697 GC B cell, M-only prime RBD pos, HTO
- GSM9640698 GC B cell, M-only prime RBD pos, BCR
- GSM9640699 PC + GC B cells, M-only prime, GEX
- GSM9640700 PC + GC B cells, M-only prime, HTO
- GSM9640701 PC + GC B cells, M-only prime, BCR
- GSM9640702 CD38+ B cell, WT prime, GEX
- GSM9640703 CD38+ B cell, WT prime, HTO
- GSM9640704 CD38+ B cell, WT prime, BCR
- GSM9640705 PC and GC B cells, WT prime, GEX
- GSM9640706 PC and GC B cells, WT prime, HTO
- GSM9640707 PC and GC B cells, WT prime BCR
- GSM9640708 CD38+ B cell, mM-only prime, GEX
- GSM9640709 CD38+ B cell, mM-only prime, HTO
- GSM9640710 CD38+ B cell, mM-only prime, BCR
- GSM9640711 GC B cell, mM-only prime RBD neg, GEX
- GSM9640712 GC B cell, mM-only prime RBD neg, HTO
- GSM9640713 GC B cell, mM-only prime RBD neg, BCR
- GSM9640714 GC B cell, mM-only prime RBD pos, GEX
- GSM9640715 GC B cell, mM-only prime RBD pos, HTO
- GSM9640716 GC B cell, mM-only prime RBD pos, BCR
- GSM9640717 PC and GC B cells, mM-only prime, GEX
- GSM9640718 PC and GC B cells, mM-only prime, HTO
- GSM9640719 PC and GC B cells, mM-only prime, BCR
- GSM9640720 GC B cell, WT prime boost RBD neg, HTO
- GSM9640721 GC B cell, WT prime boost RBD neg, BCR
- GSM9640722 GC B cell, M-only prime boost RBD neg, HTO
- GSM9640723 GC B cell, M-only prime boost RBD neg, BCR
- GSM9640724 GC B cell, mM-only prime boost RBD neg, HTO
- GSM9640725 GC B cell, mM-only prime boost RBD neg, BCR
- GSM9640726 GC B cell, WT prime boost, HTO
- GSM9640727 GC B cell, WT prime boost, BCR
- GSM9640728 GC B cell, M-only prime boost, HTO
- GSM9640729 GC B cell, M-only prime boost, BCR
+ 14 more — browse all 54 samples with per-sample file links →
- GSE242709 Global transcriptional profiles of primary and secondary cellular senescence in vivo by oncogene-induced senescence (OIS) and stress-induced senescence (SIS) 76 samples shares secondary, primary
- GSE326909 scRNAseq Dataset of lungs from WT and Clec1a KO mice following primary or secondary E. coli lung infection 12 samples shares secondary, primary
- GSE250056 Targeting chemokine crosstalk between T-cells and macrophages to treat immune checkpoint inhibito-mediated myocarditis 68 samples shares mediated
- GSE259380 TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody induces tumor regression through profound tumor microenvironment remodeling and strong antitumor adaptive immune response [RNA-seq] 149 samples shares antibody
- GSE281719 PD-1 Mediated Regulation of Unique Activated CD8+ T Cells by NK Cells in the Submandibular Gland [I15, I16] 60 samples shares mediated
- GSE327880 Neuronal activation triggers rapid biphasic FMRP-mediated translational control linking synaptic and nuclear regulation 51 samples shares mediated
- GSE286215 A temporal map of B cell diversification mechanisms in mice 35 samples shares diversification
- GSE306448 Milk osteopontin protects against infant bronchiolitis by enhancing microbiome-mediated extramedullary DC hematopoiesis 32 samples shares mediated
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.