Status Epilepticus Alters the Function of Brain-Derived Extracellular Vesicles [N2A-RNA-Seq]
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 4 × SE-BDEV-Treated vs 4 × CON-BDEV-Treated vs 4 × Vehicle-TreatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Status Epilepticus Alters the Function of Brain-Derived Extracellular VesiclesJournal of extracellular vesicles · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE327585_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1451476 and SRA study SRP690775. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9661906 SE-BDEV-Treated 1 SE-BDEV-Treated
- GSM9661907 CON-BDEV-Treated 1 CON-BDEV-Treated
- GSM9661908 SE-BDEV-Treated 2 SE-BDEV-Treated
- GSM9661909 CON-BDEV-Treated 2 CON-BDEV-Treated
- GSM9661910 SE-BDEV-Treated 3 SE-BDEV-Treated
- GSM9661911 CON-BDEV-Treated 3 CON-BDEV-Treated
- GSM9661912 SE-BDEV-Treated 4 SE-BDEV-Treated
- GSM9661913 CON-BDEV-Treated 4 CON-BDEV-Treated
- GSM9661914 Vehicle-Treated 1 Vehicle-Treated
- GSM9661915 Vehicle-Treated 2 Vehicle-Treated
- GSM9661916 Vehicle-Treated 3 Vehicle-Treated
- GSM9661917 Vehicle-Treated 4 Vehicle-Treated
- GSE327586 Status Epilepticus Alters the Function of Brain-Derived Extracellular Vesicles [BV2-RNA-seq] 9 samples shares brain-derived, extracellular, epilepticus, vesicles, status, alters
- GSE278553 Toxoplasma gondii infection of neurons alters the production and content of extracellular vesicles directing astrocyte phenotype and contributing to the loss of GLT-1 in the infected brain 15 samples shares extracellular, vesicles, alters
- GSE313455 Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles which enhance plaque clearance by microglia [RNA-Seq] 10 samples shares extracellular, vesicles
- GSE201969 In vivo self-assembly and targeted delivery of EGFR siRNA-encapsulating small extracellular vesicles to EGFR-positive cancer cells for NSCLC therapy 72 samples shares extracellular, vesicles
- GSE242731 Class switch recombination regulation by extracellular vesicles mediated intercellular epigenomic signaling 48 samples shares extracellular, vesicles
- GSE240538 A bone regenerative strategy based on extracellular vesicles transporting citrate for promoting biomineralization 37 samples shares extracellular, vesicles
- GSE240536 A bone regenerative strategy based on extracellular vesicles transporting citrate for promoting biomineralization [timepoint] 33 samples shares extracellular, vesicles
- GSE272476 Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells [RNA-seq] 30 samples shares extracellular, vesicles
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.