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Evolution of leukemic stem cell states and transcriptional programs across serial xenotransplantation in acute myeloid leukemia

GSE329505 Homo sapiens Expression profiling by high throughput sequencing 27 samples 2026/07/20 GPL24676
Summary
We performed bulk RNA-seq profiling of acute myeloid leukemia (AML) patient-derived xenograft models across serial transplantation passages (P0, P1, P2) to characterize transcriptional changes associated with leukemia propagation and stem cell activity.
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