GEO series
Transcriptomic analysis of GKB202-treated circulating tumor cells isolated from patients with lung cancer and pancreatic cancer
GSE333988
Homo sapiens
Expression profiling by high throughput sequencing
10 samples
2026/06/04
GPL18573
Summary
Circulating tumor cells (CTCs) are associated with metastatic dissemination and adaptive stress responses in cancer. In this study, patient-derived CTCs isolated from lung cancer and pancreatic cancer samples were treated with GKB202, a natural compound derived from Antrodia cinnamomea, to investigate treatment-associated transcriptomic changes. Bulk RNA sequencing was performed to compare untreated/control and GKB202-treated CTC samples. This dataset provides raw sequencing reads and processed gene-level expression matrices for evaluating the effects of GKB202 on CTC-related transcriptional programs, including stress-response and cancer-associated pathways.
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