Aptamer-Mediated Multivalent Endogenous ADAR1 Recruitment for Highly Efficient RNA Editing
RNA-seq (gene expression) · human · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 9 samples: 3 × CLUSTE vs 3 × MARRS vs 3 × ControlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE334805_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1475822 and SRA study SRP707467. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 3 replicated groups read from 9 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9797631 CLUSTER-1 CLUSTE
- GSM9797632 CLUSTER-2 CLUSTE
- GSM9797633 CLUSTER-3 CLUSTE
- GSM9797634 MARRS-1 MARRS
- GSM9797635 MARRS-2 MARRS
- GSM9797636 MARRS-3 MARRS
- GSM9797637 Control-1 Control
- GSM9797638 Control-2 Control
- GSM9797639 Control-3 Control
- GSE297017 Z-Form Stabilization By The Zα Domain Of Adar1p150 Has Subtle Effects On A-To-I Editing 39 samples shares adar1, editing
- GSE301804 Rare ADAR1 loss-of-function variants alter RNA editing and drive interferon-dependent inflammation in psoriasis 19 samples shares adar1, editing
- GSE228135 Deficiency of Smooth Muscle ADAR1 RNA Editing Exacerbates Vascular Remodeling and Pulmonary Hypertension 18 samples shares adar1, editing
- GSE87198 RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 17 samples shares adar1, editing
- GSE228133 Deficiency of Smooth Muscle ADAR1 RNA Editing Exacerbates Vascular Remodeling and Pulmonary Hypertension [pul43_RNA-seq] 12 samples shares adar1, editing
- GSE281541 Adenosine to Inosine RNA editing level in ADAR1-deficient or hypoxia-exposed human pulmonary artery endothelial cells 12 samples shares adar1, editing
- GSE285023 Biochemical Profiling and Structural Basis of ADAR1-Mediated RNA Editing 10 samples shares adar1, editing
- GSE228134 Deficiency of Smooth Muscle ADAR1 RNA Editing Exacerbates Vascular Remodeling and Pulmonary Hypertension [pul51_RNA-seq] 6 samples shares adar1, editing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.