Pioneer transcription factor TAL1 reshapes chromatin architecture to direct erythroid cell fate commitment [CUT&Tag]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 21 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 21 samples: 18 distinct titles, 3 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE337274_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1484611 and SRA study SRP714389. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 21 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9852172 Erythroid cells, TAL1 Control rep1, Day0
- GSM9852173 Erythroid cells, TAL1 Control rep2, Day0
- GSM9852174 Erythroid cells, TAL1 Control rep3, Day0
- GSM9852175 Erythroid cells, TAL1 Control rep1, Day3
- GSM9852176 Erythroid cells, TAL1 Control rep2, Day3
- GSM9852177 Erythroid cells, TAL1 Control rep3, Day3
- GSM9852178 Erythroid cells, TAL1 PROTEC_BRG1 rep1, Day7
- GSM9852179 Erythroid cells, TAL1 PROTEC_BRG1 rep2, Day7
- GSM9852180 Erythroid cells, TAL1 PROTEC_BRG1 rep3, Day7
- GSM9852181 Erythroid cells, GATA1 Control rep1, Day7
- GSM9852182 Erythroid cells, GATA1 Control rep2, Day7
- GSM9852183 Erythroid cells, GATA1 shTAL1 rep1, Day7
- GSM9852184 Erythroid cells, GATA1 shTAL1 rep2, Day7
- GSM9852185 Erythroid cells, H3K9me3 Control rep1, Day7
- GSM9852186 Erythroid cells, H3K9me3 Control rep2, Day7
- GSM9852187 Erythroid cells, H3K9me3 shTAL1 rep1, Day7
- GSM9852188 Erythroid cells, H3K9me3 shTAL1 rep2, Day7
- GSM9852189 Erythroid cells, H3K27ac Control rep1, Day7
- GSM9852190 Erythroid cells, H3K27ac Control rep2, Day7
- GSM9852191 Erythroid cells, H3K27ac shTAL1 rep1, Day7
- GSM9852192 Erythroid cells, H3K27ac shTAL1 rep2, Day7
- GSE327821 Single-molecule, single-cell profiling of linked chromatin states [Single_cell_CoCUT&Tag] 200 samples shares cut, chromatin
- GSE294275 Transcriptional analysis of direct NSD2 target genes in t(4;14) multiple myeloma reveals H3K36me2-dependent regulation and H3K27me3 antagonism [CUT&TAG] 40 samples shares cut, transcription
- GSE287902 BPTF regulstes androgen receptor activity by enhancing chromatin accessibility and stabilizing the AR-FOXA1 interaction [Cut&Run] 40 samples shares cut, chromatin
- GSE327819 Single-molecule, single-cell profiling of linked chromatin states [Bulk_CoCUT&Tag] 35 samples shares cut, chromatin
- GSE278910 Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling [CUT&RUN] 30 samples shares cut, chromatin
- GSE301512 Chromatin topology dynamics of dexamethasone-treated trabecular meshwork identifies 78 causal genes for intraocular pressure and primary open angle glaucoma [CUT&Run] 30 samples shares cut, chromatin
- GSE267470 Dual targeting of processive transcription for Myc-driven circuitry in medulloblastoma [CUT&RUN] 12 samples shares cut, transcription
- GSE178411 Whole-transcriptome analysis illustrates evolving transcriptional human response to injury in acute wounds and scars 108 samples shares cut, transcription
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.