STING Drives CD4+T Cell Differentiation via JAK-STAT Signaling in Bullous Pemphigoid
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 12 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE337832_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1491287 and SRA study SRP715948. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 12 sample titles: 12 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9861169 CD4+ T cells from BP patient 1, untreated
- GSM9861170 CD4+ T cells from BP patient 2, untreated
- GSM9861171 CD4+ T cells from BP patient 3, untreated
- GSM9861172 CD4+ T cells from healthy control 1, untreated
- GSM9861173 CD4+ T cells from healthy control 2, untreated
- GSM9861174 CD4+ T cells from healthy control 3, untreated
- GSM9861175 CD4+ T cells from BP patient 1, C176 treated
- GSM9861176 CD4+ T cells from BP patient 2, C176 treated
- GSM9861177 CD4+ T cells from BP patient 3, C176 treated
- GSM9861178 CD4+ T cells from healthy control 1, C176 treated
- GSM9861179 CD4+ T cells from healthy control 2, C176 treated
- GSM9861180 CD4+ T cells from healthy control 3, C176 treated
- GSE302339 Lung NR3C1+ and CXCR6 High CD4 T cells distinguish immunopathogenesis of human emphysema 67 samples shares sting, cd4
- GSE342431 Transcriptomic effects of combined AZD4573 and SMAP-2 treatment in resting and anti-CD3/CD28-activated primary human CD4+ T cells 12 samples shares sting, cd4
- GSE324815 Intratumoral CD40 agonist sotigalimab in combination with pembrolizumab induces rapid activation of antigen presenting cells and drives anti-tumor responses in non-injected tumors in metastatic melanoma: Results of a phase 1/2 study 24 samples shares cd4, drives
- GSE329693 Microbiome-Derived Metabolites Shape CD4⁺ T-Cell Differentiation and Immune Aging in Chronic HIV-1 Infection [RNA-Seq] 36 samples shares cd4
- GSE266884 Inhibiting macrophage-derived lactate transport restores cGAS-STING signaling and enhances anti-tumour immunity in glioblastoma 12 samples shares sting
- GSE267774 Specific CD4+ T cell phenotypes associate with bacterial control in people who ‘resist’ infection with Mycobacterium tuberculosis 3076 samples shares cd4
- GSE279480 Longitudinally stable T cell and innate immune activity distinguish healthy adult immunotypes I 1021 samples shares sting
- GSE242232 Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases 928 samples shares cd4
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.