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Single-cell RNA-seq of synovial fluid cells from osteoarthritis control patients

GSE338779 Homo sapiens Expression profiling by high throughput sequencing 3 samples Submitted 2026/07/22 Platform GPL24676
Summary
This dataset contains processed 10x Genomics single-cell RNA-seq data from synovial fluid cells of three treatment-naive osteoarthritis (OA) patients. These OA samples were used as controls in the published Nature Communications study "Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF/JAK inhibitor treatment" (doi: 10.1038/s41467-025-57361-0), which profiled synovial fluid immune cells to characterize rheumatoid arthritis-associated cellular states and treatment-related immune remodeling.
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Direct links to NCBI, no account and no request form: the whole study as GSE338779_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 3 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1495863. Searching any of these in the dataset finder brings you back here.

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