EKLF/KLF1 coordinates specialized transcriptional networks required to maintain the integrity of terminal erythropoiesis
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × knockout, differentiation d2, vs 3 × wild type, differentiation d2, vs 3 × knockout, expansion, vs 3 × wild type, expansion,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- KLF1 coordinates specialized transcriptional networks required to maintain the integrity of terminal erythropoiesisJournal of cell science · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE338783_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1495869 and SRA study SRP718347. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 6 samples read as cases, 6 as controls.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9881395 knockout, differentiation d2, replicate 1 knockout, differentiati…
- GSM9881396 knockout, differentiation d2, replicate 2 knockout, differentiati…
- GSM9881397 knockout, differentiation d2, replicate 3 knockout, differentiati…
- GSM9881398 wild type, differentiation d2, replicate 1 wild type, differentiat…
- GSM9881399 wild type, differentiation d2, replicate 2 wild type, differentiat…
- GSM9881400 wild type, differentiation d2, replicate 3 wild type, differentiat…
- GSM9881401 knockout, expansion, replicate 1 knockout, expansion,
- GSM9881402 knockout, expansion, replicate 2 knockout, expansion,
- GSM9881403 knockout, expansion, replicate 3 knockout, expansion,
- GSM9881404 wild type, expansion, replicate 1 wild type, expansion,
- GSM9881405 wild type, expansion, replicate 2 wild type, expansion,
- GSM9881406 wild type, expansion, replicate 3 wild type, expansion,
- GSE278050 KLF13 promotes SLE Pathogenesis by modifying chromatin accessibility of key proinflammatory cytokine genes [RNA-seq] 42 samples shares klf1
- GSE199288 Perivascular fibrosis is mediated by a KLF10-IL-9 signaling axis in CD4+ T cells 27 samples shares klf1
- GSE240553 Missense mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins to cause hemolysis 18 samples shares klf1
- GSE269020 FOXO1-KLF10 reinforcing loop promotes adipose lipolysis to facilitate exercise-induced anti-obesity effect in male mice 8 samples shares klf1
- GSE315590 Single-cell transcriptomic analysis of KLF15-mediated cardiac protection in heart failure 6 samples shares klf1
- GSE278051 KLF13 promotes SLE Pathogenesis by modifying chromatin accessibility of key proinflammatory cytokine genes 70 samples shares klf1
- GSE278048 KLF13 promotes SLE Pathogenesis by modifying chromatin accessibility of key proinflammatory cytokine genes [ATAC-seq] 28 samples shares klf1
- GSE94351 Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis 13 samples shares klf1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.