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Bulk RNA sequencing of human forebrain organoids following Aβ42 treatment

GSE339404 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/07/26 Platform GPL29480
Summary
Human iPSC-derived forebrain organoids were exposed to amyloid-β42 (Aβ42) at day90 to model Alzheimer's disease-associated pathology. Bulk RNA sequencing was performed to characterize transcriptional changes induced by Aβ42 treatment. The resulting dataset provides genome-wide expression profiles of treated and untreated organoids.
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Direct links to NCBI, no account and no request form: the whole study as GSE339404_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1498598 and SRA study SRP720016. Searching any of these in the dataset finder brings you back here.

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