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Direct reprogramming of human fibroblasts to functional hepatocyte-like cells

GSE42643 Homo sapiens Expression profiling by array 13 samples Submitted 2014/03/06 Platform GPL4133
Summary
Plasticity of differentiated cells has been proved by nuclear transfer, induced pluripotent cells and transdifferentiation. Here we show that by transduction of 3 factors (FOXA3, HNF1A and HNF4A), human fetal fibroblasts can be converted to hepatocyte-like cells (hiHep cells), expressing hepatic marker genes, and acquiring many mature hepatocyte functions in vitro and in vivo.
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Also filed as BioProject PRJNA182503. Searching any of these in the dataset finder brings you back here.

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