GEO series

Gene expression profile analysis of mouse whole spleen following infection by lymphocytic choriomeningitis virus (LCMV), comparing LCMV-Armstrong and LCMV-Clone 13 expression patterns at 0, 5, 9, and 30 days

GSE44322 Mus musculus (mouse) Expression microarray 26 samples Submitted 2013/02/15 Platform GPL6246

At a glance

Expression microarray · mouse · 26 samples

What it is: Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
Organism: Mus musculus (mouse)
Samples: 26 samples
Data you can get: A processed expression table (series matrix) and the array files, from NCBI.

Summary (written by the submitters)

To identify mechanisms behind immunosuppression during virus infections, we infected mice with LCMV-Armstrong and LCMV-Clone 13 expression patterns. LCMV-Armstrong induces a T-cell reaction that resolves infection within 8-10 days, while LCMV-Clone13 generates a persisten infection through immunosuppression. We used microarray to uncover splenic gene expression patterns specific to each LCMV infection at 5, 9, and 30 days

This dataset

Open GSE44322 in finder → Find more mouse microarray datasets →

Download · which file do I need?

Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need.

All supplementary files ↗

3 · The original raw files

Whole study · RAW.tar

Everything the authors deposited as one archive (GSE44322_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.

Whole study · RAW.tar ↓

What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.

Also filed as BioProject PRJNA189457. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 23580528) ↗

Samples in this study

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+ 26 more — browse all 26 samples with per-sample file links →

Datasets on a similar topic

GSE86796 Expression data from CD8 T cells from LCMV-Clone13 infected mice after two weeks of control or anti-PD-L1 treatment 8 samples shares lcmv, lcmv-clone
GSE86881 Transcriptional profiles of virus-specific CD8+ T cells from control or anti-PD-L1-treated LCMV-Clone 13 infected mice one day or 18-29 weeks after treatment 13 samples shares lcmv, lcmv-clone
GSE226067 scATAC-seq of antigen-specific CD8+ T cells from different time-course of LCMV-Armstrong infected mice 5 samples shares lcmv, lcmv-armstrong
GSE8678 Gene expression data from sorted IL-7Rhi/lo effector CD8 T cells on day 6/7 after LCMV armstrong infection 6 samples shares lcmv
GSE245436 The efficacy of LCMV-based cancer vaccines is unleashed by intratumoral injections of polyI:C 36 samples shares lcmv
GSE301271 Pan organ and time course analysis of T cells in acute LCMV (armstrong) infection (day 7) [I36] 30 samples shares lcmv
GSE301960 Pan organ and time course analysis of T cells in acute LCMV (armstrong) infection (day 30) [I38] 30 samples shares lcmv
GSE301961 Pan organ and time course analysis of T cells in acute LCMV (armstrong) infection (day 60) [I40] 30 samples shares lcmv

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