m6A-dependent regulation of messenger RNA stability
RNA-seq (gene expression) · human · 29 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 29 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE49339_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA213675 and SRA study SRP028325. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 29 more — browse all 29 samples with per-sample file links →
- GSE301535 Integrative analysis of mRNA stability regulation uncovers a metastasis-suppressive program in breast cancer 36 samples shares stability
- GSE219125 m6A modification governs the stability of both methylated and unmethylated mRNA isoforms across the transcriptome 162 samples shares stability
- GSE225951 A dual role of EZH2 in regulating A-to-I RNA editing and mRNA stability through ADAR1 75 samples shares stability
- GSE239892 Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis 21 samples shares m6a-dependent
- GSE240879 FTO-mediated autophagy inhibition promotes non-small cell lung cancer progression by reducing SESN2 mRNA stability [MeRIP-Seq] 12 samples shares stability
- GSE246521 Chronic Lymphocytic Leukemia in African Ancestry Population is Characterized by Increased Genomic Instability 350 samples shares stability
- GSE94613 Promoter-bound METTL3 maintains myeloid leukemia by m6A-dependent regulation of protein translation 42 samples shares m6a-dependent
- GSE325326 Codon-dependent regulation of mRNA translation and stability by ZC3H7A and ZC3H7B RNA-binding proteins 24 samples shares stability
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.