Gene expression analysis of estrogen receptor mutants, S463P, Y537S and D538G in MCF7 cells
Expression microarray · human · 36 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Samples
- 36 samples
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE51448_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA223675. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 36 more — browse all 36 samples with per-sample file links →
- GSE281302 ESR1 Y537S and D538G mutations drive resistance to CDK4/6 inhibitors in estrogen receptor-positive breast cancer 36 samples shares y537s, d538g, estrogen, receptor
- GSE336731 Transcriptomic profiling of MCF7 ESR1-PARENT and ESR1-Y537S cells cultured under estrogen-depleted or estradiol-supplemented conditions following abemaciclib treatment and CCND1 knockdown 36 samples shares y537s, mcf7, estrogen
- GSE210007 Estrogen Receptor alpha CUT&RUN analysis of estrogen receptor positive breast cancer cell lines MCF7 and UCD12 with 1h hormone E2 treatment 40 samples shares mcf7, estrogen, receptor
- GSE307693 Transcriptomic profiling in estrogen-receptor positive cell line MCF7 following treatment with abemaciclib and fulvestrant 24 samples shares mcf7, estrogen, receptor
- GSE303328 Rb CUT&RUN profiling in estrogen receptor-positive breast cancer cell line MCF7 following palbociclib treatment 5 samples shares mcf7, estrogen, receptor
- GSE336734 Transcriptomic profiling of MCF7 ESR1 Y537S mutant cells treated with abemaciclib and/or fulvestrant 8 samples shares y537s, mcf7
- GSE225423 Bulk and single cell RNA-seq of MCF7 and MCF7 TDP2-KO cells treated with/without estrogen 16 samples shares mcf7, estrogen
- GSE13733 Effects of DZNep and 5-Aza-CdR on gene expression in MCF7 cells 10 samples shares mcf7
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.