GEO series

Expression data from undifferentiated human ES cell line, khES3, grown using complete or methionine deprived media and ES cell derived endoderm

GSE55283 Homo sapiens Expression profiling by array 6 samples Submitted 2014/04/17 Platform GPL570

Summary

In undifferentiated human ES cells, 5hr Met deprivation (delta Met) led to decreased proliferation, and prolonged 24hr Met deprivation resulted in G0-G1 phase cell cycle arrest, which then led to apoptosis. We used microarrays to detail the molecular mechanism of cell-death caused by Met deprivation in undifferentiated ES cells and checked the difference of Met cycle relate gene expression between undifferentiated human ES cells and ES cell derived endoderm.

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Direct links to NCBI, no account and no request form: the whole study as GSE55283_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA239200. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 24746804) ↗

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