Genome-wide analysis of gene expression in lung cells from metformin treated Mycobacterium tuberculosis infected mice
Expression microarray · mouse · 14 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 5 × day 30, infected + metformin treated vs 3 × day 30, infected vs 3 × uninfectedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE57275_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA246153. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 11 samples.
How we read this: 3 replicated groups read from 14 sample titles; they account for 11 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM1378192 day 30, infected_1 day 30, infected
- GSM1378193 day 30, infected_2 day 30, infected
- GSM1378194 day 30, infected_2_rep
- GSM1378195 day 30, infected_3 day 30, infected
- GSM1378196 day 30, infected + metformin treated_1 day 30, infected + metf…
- GSM1378197 day 30, infected + metformin treated_2 day 30, infected + metf…
- GSM1378198 day 30, infected + metformin treated_3 day 30, infected + metf…
- GSM1378199 day 30, infected + metformin treated_4 day 30, infected + metf…
- GSM1378200 day 30, infected + metformin treated_5 day 30, infected + metf…
- GSM1378201 uninfected_2 uninfected
- GSM1378202 uninfected_2_rep
- GSM1378203 uninfected_3 uninfected
- GSM1378204 uninfected_4 uninfected
- GSM1378205 uninfected_4_rep
- GSE263892 Single-cell analysis reveals Mycobacterium tuberculosis ESX-1-mediated accumulation of permissive macrophages in infected mouse lungs 6078 samples shares mycobacterium, tuberculosis, infected, lung
- GSE263891 Single-cell analysis reveals Mycobacterium tuberculosis ESX-1–mediated accumulation of permissive macrophages in infected mouse lungs 6072 samples shares mycobacterium, tuberculosis, infected, lung
- GSE255689 Core immunometabolic reprogramming of Mycobacterium tuberculosis-infected mouse lungs and stage-specific effects by glutamine supplementation 24 samples shares mycobacterium, tuberculosis, infected, lung
- GSE289356 Effects of type I IFN signaling on gene expression of Mycobacterium tuberculosis-infected bone marrow-derived macrophages (BMDMs) 34 samples shares mycobacterium, tuberculosis, infected
- GSE290804 Comparative Transcriptomic Analysis of Mouse Macrophages Infected with Live Attenuated Vaccine Strains of Mycobacterium tuberculosis 32 samples shares mycobacterium, tuberculosis, infected
- GSE255565 Transcriptional response in RAW 264.7 macrophages infected with zinc-replete and zinc-limited Mycobacterium tuberculosis 24 samples shares mycobacterium, tuberculosis, infected
- GSE291405 Transcriptomic profiling of mouse macrophages treated with recombinant Rv0009, a secretory protein of Mycobacterium tuberculosis 12 samples shares mycobacterium, tuberculosis, treated
- GSE315842 Cytomegalovirus as a risk factor for exacerbation of Mycobacterium tuberculosis: development of a Mtb-CMV mouse model infection 54 samples shares mycobacterium, tuberculosis
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.