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RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells

GSE57488 Homo sapiens Expression profiling by high throughput sequencing 12 samples Submitted 2014/08/05 Platform GPL11154
Summary
Our studies indicate that glucose and acetate can regulate histone acetylation by altering the acetyl-CoA concentrations in the cell. The purpose of this study was to to determine whether specific gene sets correlated with acetyl-CoA availability. We conclude that 10% of glucose-regulated genes are acetyl-CoA regulated genes (genes suppressed or induced by low glucose and reversed by acetate). Acetate usually regulated gene expression in the same direction as glucose, suggesting that acetyl-CoA is a key mediator of glucose-dependent gene expression.
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Also filed as BioProject PRJNA246544 and SRA study SRP041825. Searching any of these in the dataset finder brings you back here.

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