GEO series

Genome Wide Characterization of Genome Organization in Mouse ES cells

GSE64881 Mus musculus; other sequences Genome variation profiling by high throughput sequencing; Other 477 samples Submitted 2017/03/08 Platform GPL19736Platform GPL13112

Summary

The three-dimensional folding of genomes in the eukaryotic nucleus can influence the expression of genes. We used a new method to determine interactions between different chromatin regions genome-wide. Using a simple statistical model, we determine the subset of those interactions which represent stable contacts. We find an enrichment in contacts between active genes, between Polycomb-repressed genes, between enhancer elements and between enhancers and active genes.

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Direct links to NCBI, no account and no request form: the whole study as GSE64881_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 477 samples. Raw sequencing reads are also available from ENA.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗ Raw reads on ENA ↗

Also filed as BioProject PRJNA272507 and SRA study SRP052060. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 28273065) ↗

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