Epigenetic inflexibility of exhausted T cells limits durability of reinvigoration by PD-1 blockade
Direct links to NCBI, no account and no request form: the whole study as GSE86797_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 10 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA342526 and SRA study SRP088651. Searching any of these in the dataset finder brings you back here.
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- GSE289108 Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptic remodeling in the inflamed brain [ChIP-Seq] 57 samples
- GSE298001 Stage-specific Epigenetic Priming Amplifies Gene Activation During Lineage Commitment [ATAC-Seq] 36 samples
- GSE337898 ATAC-seq profiling of lineage-traced exhausted and memory-like CD8+ T cell subsets during tumor progression 24 samples
- GSE275917 Nup153 regulates neuronal responsiveness through HDAC1-mediated epigenetic modulation [ChIP-seq] 17 samples
- GSE271883 Maternal high-fat diet alters Tet-mediated epigenetic regulation during heart development [ATAC-Seq] 12 samples
- GSE254919 Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy [ATAC-seq] 12 samples
- GSE331488 A global view of cell-type-specific temporal dynamics in mammalian aging [I] 771 samples
- GSE331489 A global view of cell-type-specific temporal dynamics in mammalian aging [II] 725 samples
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