Epigenetic analysis of tumor-specific CD8 T cells in murine and solid tumors
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 59 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 59 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE89308_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA351717 and SRA study SRP092279. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 59 more — browse all 59 samples with per-sample file links →
- GSE333858 PD-1 regulates latent effector differentiation of thymic cytotoxic CD8+ T cells 74 samples shares cd8
- GSE255177 Inhibiting CXCR4 Attenuates TOX-Programmed Exhausted Phenotype of CD8+ T cells via Regulating JAK2/STAT3 Pathway [ChIP-Seq] 20 samples shares cd8
- GSE261093 The TET2 methylcytosine dioxygenase regulates early and late transitions in exhausted CD8+ T-cell differentiation 51 samples shares cd8
- GSE235246 Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma impair CD8+ T cell activation and responsiveness to immunotherapy in mice 38 samples shares cd8
- GSE235233 Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma suppress CD8+ T cell activation and inhibit response to immune checkpoint therapy [Cultured_Human_Mouse] 16 samples shares cd8
- GSE314446 Human GPR15 deficiency reveals CD8+ T regulatory cell-macrophage crosstalk in intestinal inflammation 16 samples shares cd8
- GSE260599 Anti-tumor activity of a novelLAIR1antagonist in combination with anti-PD-1to treat collagen-rich solid tumors 61 samples shares solid
- GSE266298 Epigenetic changes by EZH2 inhibition increase translocations in B cells with high AID activity or DNA repair deficiency 130 samples shares epigenetic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.