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Epigenetic analysis of tumor-specific CD8 T cells in murine and solid tumors

GSE89308 Homo sapiens; Mus musculus Genome binding/occupancy profiling by high throughput sequencing; Other 59 samples Submitted 2017/05/17 Platform GPL17021Platform GPL16791
Summary
ATACseq analysis of dysfunctional CD8 T cells in progressing tumors. The overall goal of this study was to elucidate chromatin states associated with functional unresponsiveness in tumor-specific CD8 T cells in the context of mouse and human tumors. As comparison we also investigated chromatin state dynamics associated with CD8 T cells differentiation to functional effector and memory T cells during an acute listeria infection.
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Also filed as BioProject PRJNA351717 and SRA study SRP092279. Searching any of these in the dataset finder brings you back here.

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