Bone-marrow-derived mesenchymal stem cells promote breast cancer metastasis
Expression microarray · human · 22 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Topic
- Breast cancerThis series is part of our curated briefing on it.
- Samples
- 22 samples: 22 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE8977_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA102435. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 7 samples read as cases, 15 as controls.
How we read this: Read from 22 sample titles: 22 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM227514 Stroma normal breast (NS1)
- GSM227515 Stroma normal breast (NS10)
- GSM227516 Stroma normal breast (NS2)
- GSM227517 Stroma normal breast (NS3)
- GSM227518 Stroma normal breast (NS4)
- GSM227519 Stroma normal breast (NS5)
- GSM227520 Stroma normal breast (NS6)
- GSM227521 Stroma normal breast (NS7)
- GSM227522 Stroma normal breast (NS768)
- GSM227523 Stroma normal breast (NS8)
- GSM227524 Stroma normal breast (NS817)
- GSM227525 Stroma normal breast (NS9)
- GSM227526 Stroma normal breast (Nstr101904)
- GSM227527 Stroma normal breast (Nstr112204)
- GSM227528 Stroma normal breast (Nstr122204)
- GSM227529 Stroma tumor (TS718)
- GSM227530 Stroma tumor (TS795)
- GSM227531 Stroma tumor (TS816)
- GSM227532 Stroma tumor (TS817)
- GSM227533 Stroma tumor (TS818)
- GSM227534 Stroma tumor (TS820)
- GSM227535 Stroma tumor (TS838)
- GSE11121 The humoral immune system has a key prognostic impact in node-negative breast cancer 200 samples same disease briefing · shares breast, stem
- GSE10886 A Supervised Risk Predictor of Breast Cancer Based on Biological Subtypes 226 samples same disease briefing · shares breast
- GSE104193 Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signalling and malignant features in vitro and in vivo 32 samples same disease briefing · shares breast
- GSE104675 Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 6 samples same disease briefing · shares breast
- GSE10885 An integromic analysis reveals that metaplastic carcinomas are distinct from basal-like tumors. 244 samples same disease briefing
- GSE253036 Tumor Cell JAGGED-1 Promotes Lymph Node Metastasis and Predicts Recurrence in Lymph Node Positive Breast Cancer Patients 27 samples shares metastasis, promote, breast
- GSE278450 Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells 22 samples shares mesenchymal, stem
- GSE266330 Single cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization 63 samples shares metastasis, stem
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.