Dissecting immune circuits by linking CRISPR pooled screens with single cell RNA-seq
Direct links to NCBI, no account and no request form: the whole study as GSE90488_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 70 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA354864 and SRA study SRP093880. Searching any of these in the dataset finder brings you back here.
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- GSE334890 Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors 48 samples
- GSE263761 Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation [CROP-seq KO150] 27 samples
- GSE215963 Subclonal evolution revealed by single-cell profiles of expressed mutations identifies adaptation mechanisms to immunotherapy in melanoma. 1497 samples
- GSE312107 PerturbPair: A Dual-Modality Platform Integrating Perturb-seq and Optical Pooled Screening to Map Cellular Responses and Enable Cross-Modal Inference 70 samples
- GSE250056 Targeting chemokine crosstalk between T-cells and macrophages to treat immune checkpoint inhibito-mediated myocarditis 68 samples
- GSE269045 Inflammatory immune modulators of AML lung infiltration and respiratory failure 56 samples
- GSE326797 Antibody Mediated Diversification of Primary and Secondary Humoral Immune Responses 54 samples
- GSE294093 Single-cell transcriptomics and translatomics dual-omics analysis reveals the potential mechanism of HFD-induced maternal RNA degradation abnormalities 42 samples
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