Global transcriptional profiling confirmed failed decidualization of human Endometrial Stromal Cells (hESCs) obtained from non-pregnant women with a previous pregnancy complicated by severe preeclampsia (sPE).
Expression microarray · human · 20 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 20 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE91077_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA356828. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 20 sample titles: 20 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM2420587 Normal pregnancy 1_ Non decidualized
- GSM2420588 Normal pregnancy 2_ Non decidualized
- GSM2420589 Normal pregnancy 2_ Decidualized
- GSM2420590 Normal pregnancy 3_ Non decidualized
- GSM2420591 Normal pregnancy 3_ Decidualized
- GSM2420592 Normal pregnancy 4_ Non decidualized
- GSM2420593 Normal pregnancy 4_ Decidualized
- GSM2420594 Normal pregnancy 5_ Non decidualized
- GSM2420595 Normal pregnancy 6_ Non decidualized
- GSM2420596 Normal pregnancy 6_ Decidualized
- GSM2420597 Normal pregnancy 7_ Non decidualized
- GSM2420598 Normal pregnancy 7_ Decidualized
- GSM2420599 Severe Preeclampsia 1_Decidualized
- GSM2420600 Severe Preeclampsia 2_Non Decidualized
- GSM2420601 Severe Preeclampsia 2_Decidualized
- GSM2420602 Severe Preeclampsia 3_Non Decidualized
- GSM2420603 Severe Preeclampsia 3_Decidualized
- GSM2420604 Severe Preeclampsia 4_Non Decidualized
- GSM2420605 Severe Preeclampsia 4_Decidualized
- GSM2420606 Severe Preeclampsia 6_Decidualized
- GSE306127 Impact of vitamin D deficiency on defective endometrial decidualization and the repressive role of VDR in the epigenomic network [CUT&Run] 48 samples shares decidualization, endometrial
- GSE295760 Multi-omics of chorionic villus samples reveals early pregnancy placental dysfunction associated with preeclampsia 38 samples shares preeclampsia, pregnancy
- GSE272778 Analysis of endometrial mRNA in patients with different pregnancy outcomes after immunotherapy: A cohort study 29 samples shares endometrial, pregnancy
- GSE263305 Analysis of retroviral MLT1 enhancer-driven genes identifies over-expression of EPS8L1 as an early-stage initiator of both oxidative stress and poor trophoblast invasiveness in the pregnancy disorder preeclampsia 24 samples shares preeclampsia, pregnancy
- GSE265862 Mapping Decidualization Resistance in Former Severe Preeclampsia Patients at Multi-Omic Levels 23 samples shares decidualization, preeclampsia
- GSE325553 Comparative transcriptomic profiling of human 3D endometrial stromal organoids under distinct decidualization stimuli 20 samples shares decidualization, endometrial
- GSE287645 Maternal cause of early-onset preeclampsia: excessive endometrial gland-derived apolipoprotein D induces placental ferroptosis and developmental abnormalities 16 samples shares preeclampsia, endometrial
- GSE306844 Nicotinamide counteracts endothelin-1’s detrimental effect on uterine decidualization during early pregnancy by influencing EDNRB 15 samples shares decidualization, pregnancy
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.