Heterogeneity in neurodegenerative disease
RNA-seq (gene expression) · human · 117 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 117 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE95587_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA377568 and SRA study SRP100948. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 117 more — browse all 117 samples with per-sample file links →
- GSE263786 Epigenetic heterogeneity hotspots in human liver disease progression [RNA-seq] 243 samples shares heterogeneity
- GSE319666 Archetype analysis of lung adenocarcinoma premalignancy links heterogeneity in premalignant lesions to diverging features of invasive disease 177 samples shares heterogeneity
- GSE245175 Neuroblastoma heterogeneity and plasticity over disease progression are rooted in the dynamics of an early sympathetic transcriptional trajectory 79 samples shares heterogeneity
- GSE318560 Common pathogenic mechanisms in the hippocampus across neurodegenerative dementias: Alzheimer's disease, Down syndrome, and Parkinson's disease 20 samples shares neurodegenerative
- GSE220774 Side- and disease-dependent changes in human aortic valve cell population and transcriptomic heterogeneity determined by single-cell RNA sequencing 15 samples shares heterogeneity
- GSE319175 A Comprehensive Adenoid Cystic Carcinomas-Derived Organoid Platform for Disease Modeling and Drug Screening Captures Interpatient Heterogeneity 12 samples shares heterogeneity
- GSE228033 A single-cell atlas revealing cellular heterogeneity across healthy and diseased human thymus 10 samples shares heterogeneity
- GSE273146 Patient-derived liver organoids recapitulate epithelial heterogeneity and enable precision disease modelling of alcohol-associated liver disease 10 samples shares heterogeneity
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.