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Non-demented individuals with intermediate Alzheimer's neuropathologies - neuronal expression (6 regions)

GSE9770 Homo sapiens (human) Expression microarray 34 samples Submitted 2007/12/05 Platform GPL570
At a glance

Expression microarray · human · 34 samples

What it is
Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
Organism
Homo sapiens (human)
Samples
34 samples: 6 conditions, mostly with about 6 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed expression table (series matrix) and the array files, from NCBI.
Summary (written by the submitters)
Layer II stellate neurons (entorhinal cortex) and layer III cortical neurons (hippocampus CA1, middle temporal gyrus, posterior cingulate, superior frontal gyrus, primary visual cortex) were gene expression profiled. Brain regions are from non-demented individuals with intermediate Alzheimer's disease neuropathologies Keywords: neuronal gene expression profiling
This dataset
Open GSE9770 in finder → Find more human microarray datasets →
Download · which file do I need?

Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓
2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need.

All supplementary files ↗
3 · The original raw files

Whole study · RAW.tar

Everything the authors deposited as one archive (GSE9770_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.

Whole study · RAW.tar ↓

What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.

Also filed as BioProject PRJNA103705. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 29937276) ↗
Study design
6 conditions, mostly with about 6 replicates each
non-demented individual with intermediate Alz… ×6 non-demented individual with intermediate Alz… ×6 non-demented individual with intermediate Alz… ×6 non-demented individual with intermediate Alz… ×6 non-demented individual with intermediate Alz… ×5 non-demented individual with intermediate Alz… ×5

Supports a between-group comparison across 34 samples.

How we read this: 6 replicated groups read from 34 sample titles; they account for 34 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study
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