GEO series
Large-scale tethering of RNA binding proteins discovers alternative splicing regulators [RIP-Seq]
GSE100637
Homo sapiens
Expression profiling by high throughput sequencing
48 samples
2025/04/27
GPL20301
Summary
To elucidate the role of large sets of RBPs, we developed a comprehensive and diverse plasmid resource3 of 765 RBPs fused to the MS2 bacteriophage coat protein. When systematically tethered to an intronic 4 MS2 hairpin downstream ofan alternative exon, we identified 55 RBPs that significantly induced exon 5 retention.
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