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Olig2 targetome in SHH subgroup of medulloblastoma

GSE103824 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2024/03/23 Platform GPL17021
Summary
Several basic helix-loop-helix (bHLH) transcription factors are upregulated in Sonic Hedgehog subgroup of medulloblastoma (SHH MB). Olig2, a neural bHLH transcription factor known to regulate differentiation of neural cell populations, is broadly expressed in mouse models of SHH MB. ChIP-Seq of Olig2 revealed its binding to a large number of sites near genes known to promote SHH MB tumorigenesis, suggesting a potential role for Olig2 in regulating transcriptional programme of MB.
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Direct links to NCBI, no account and no request form: the whole study as GSE103824_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA407111 and SRA study SRP117605. Searching any of these in the dataset finder brings you back here.

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